Countless people benefit from pharmaceutical drugs to treat their IC. Additionally, countless people move from treatment protocol to treatment protocol and do not find much relief from their IC pain and symptoms. I wonder and worry though about the countless laboratory animals that will continue to be subjected not only to the markers that cause IC, but to countless protocols of drugs to try and treat the IC, all the while measuring, manipulating and storing the data. These animals do not have a voice. As a human with IC, I have a choice about my treatment plan, and I can voice my pain and discomfort. I can talk to a friend or meet someone else with IC. I can blog about my pain living with IC. These poor animals are subjected to the pain and then left to sleep in their wire cages until the next morning when the researchers return to the laboratory. Food for thought, ICers. That is all I, and the animals, can hope for at this point.